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1. Continuous culture has an advantage over to a batch cultures as
(A): all of the above
(B): cells can be maintained at a constant physiological state simply by setting the dilution rate
(C): continuous reactors do not need to be shut down and cleaned as regularly as a batch reactor
(D): most downstream and upstream processes are continuous in nature and thus the operation of continuous bioreactor can be better integrated into the overall manufacturing process
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